KeyScreen™ GI Parasite PCR Fecal Test for Dogs & Cats

Detects what others miss

What is KeyScreen™ GI Parasite PCR?

KeyScreen™ is a cutting-edge gastrointestinal (GI) parasite test that uses PCR to identify parasite genetic material in veterinary fecal samples from dogs and cats.

Why Molecular PCR Testing is Superior to Traditional Methods

Limitations of O&P and ELISA

Screening for GI parasites hasn’t changed much in decades. O&P (ova and parasites) and ELISA testing have strengths, but they also have inherent limitations such as relying on visual identification and requiring large sample sizes.

When there’s no guarantee that parasites (or their eggs) will be present even in an adequately sized sample, more precise screening methods like PCR testing help identify parasites effectively.

Precision of PCR Detection

KeyScreen uses real-time quantitative Polymerase Chain Reaction (qPCR), a sensitive molecular detection method, to identify and amplify genetic material from parasites. This includes microscopic parasite material, such as eggs and cells, the protective outer covering of worm species like tapeworms, and cells from different life stages of protozoa. KeyScreen then reports out which parasites have been found in the fecal sample, the parasite burden (low, medium, or high), and the presence of any co-infections — including 2.5x more co-infections than in-clinic fecal flotations alone.2

What Parasites Does KeyScreen Detect?

KeyScreen detects 20 intestinal parasites, benzimidazole resistance in hookworms, and determines the zoonotic potential of Giardia..

Ankylostomes
  • Ancylostome espèces
  • A. caninum benzimidazole resistance marker
  • Uncinaria stenocephala
Vers ronds
  • Toxocara espèces
  • Toxocara canis
  • Toxocara cati
  • Toxascaris leonina
  • Baylisascaris procyonis
Trichocéphales
  • Trichuris vulpis
Giardia.
  • Giardia duodénal
  • Giardia. zoonotic strains A & B marker
Coccidia
  • Cystoisospora espèces
  • Eimeria espèces
Ténias
  • Dipylidium caninum
  • Echinococcus multilocularis
  • Echinococcus granulosus
  • Ténia espèces
Additional Protozoa
  • Neospora caninum
  • Toxoplasma gondii
  • Tritrichomonas blagburni
  • Cryptosporidium canis
  • Cryptosporidium felis

KeyScreen Sample Requirements & Turnaround Times

Fast, Comprehensive Screening; One Small Sample Size

Échantillon (volume)
0,15 gramme de matières fécales
Can be stored for 10 days with refrigeration

Délai
24 heures pour la plupart des clients. 48 heures ou moins pour tous les clients.

Code américain
KeyScreen Parasite gastro-intestinal PCR : T991

Code du Canada
KeyScreen Parasite gastro-intestinal PCR : CT991

Benefits for Your Practice & Patients

Regular parasite screening with KeyScreen helps keep your patients healthier in alignment with recommended screening guidelines and responsible treatment approaches.

The independent Companion Animal Parasite Council (CAPC) recommends testing for gastrointestinal parasites at least four times in the first year of life for puppies and kittens and at least two times per year in adult dogs and cats, depending on patient health and lifestyle factors.1 By using KeyScreen to inform treatment decisions — prescribing mindfully and not using medication when it’s not indicated — you’re actively participating in antimicrobial stewardship and upholding a commitment to One Health.

KeyScreen aide les vétérinaires à obtenir de meilleurs résultats en matière de santé pour leurs patients et les propriétaires d'animaux de compagnie.

Le test Antech KeyScreen™ a complètement changé notre perception des parasites et de leur traitement. Grâce à ce test, nous détectons plus de parasites positifs que jamais, surtout si l'on compare aux limites de la détection par flottation fécal. Nous pouvons désormais mieux aider nos clients à comprendre les risques pour leur santé en les différenciant. Baylisascaris procyonis et les différentes souches de Giardia.L'innovation apportée par ce test a modifié le profil des parasites observés ; nous disposons manitenant d'une meilleure capacité de diagnostic. Nous savons désormais que notre population est effectivement atteinte du gène Giardia zoonotique. Nous avons également détecté des parasites jamais observés auparavant en clinique, comme trichuris vulpis et cryptosporidium. KeyScreen a considérablement amélioré notre capacité à servir nos clients en fournissant une meilleure solution pour les tests de parasites et le traitement ultérieur.

Robert Burns, vétérinaire – Hôpital vétérinaire de Darlington

Le test KeyScreen a complètement transformé notre approche du diagnostic parasitaire. Je n'avais pas réalisé la complexité et les lacunes de notre ancien processus de dépistage des parasites gastro-intestinaux avant de commencer à utiliser le KeyScreen. L'impact de la précision et de la rapidité de ce test va bien au-delà du diagnostic initial. Le KeyScreen nous a permis de proposer des options de traitement plus rapidement et en toute confiance aux propriétaires d'animaux, et son flux de travail a permis à mon équipe de gagner un temps précieux.

Rhonda Daniels, vétérinaire – Vétérinaires du nord du Texas

Ressources KeyScreen

KeyScreen FAQs for Clinicians

Is KeyScreen for sick patients or patients without clinical signs?

KeyScreen is perfect for all clinical presentations, including routine wellness screenings. Because many parasitic infections can cause non-specific clinical signs, or can be asymptomatic, PCR testing with KeyScreen is the best way to detect all genetic material from parasites that might be in a fecal sample — down to the molecular level.

What can KeyScreen tell me about zoonotic Giardia?

Giardia. is the most common intestinal parasitic disease in the U.S., affecting more than one million people per year. Children, the elderly, and the immunocompromised are at much higher risk for Giardia. infection and have higher infection rates. Because some strains of Giardia. have the potential to infect humans, it’s essential to know whether your patients have Giardia. from these zoonotic assemblages (A/B), so you can determine the best course of treatment and inform clients about their human family’s level of risk.

Why is it important to know about the parasite down to the species name?

Knowing the exact parasite species present in a sample means you can make an informed decision about treatment. For example, most tapeworm infections can be visibly diagnosed due to the segments (proglottids) found in the fecal sample or around the patient’s perianal area.


KeyScreen rapidly helps you decipher if the infection is due to Dipylidium caninum, in which the intermediate hosts are flea/lice, or due to Ténia spp. from eating rabbit or ruminant tissues. These different tapeworms have unique life cycles, meaning you need to know the intermediate host (flea/lice, rabbit, ruminant, etc.) to address the infection and to treat properly. 

How will using KeyScreen for parasite screening help me combat antimicrobial resistance?

As the most sensitive intestinal parasite screening panel in veterinary medicine, KeyScreen helps veterinarians to strengthen their commitment to One Health priorities — specifically, pharmacological stewardship and the responsible use of anthelmintic drugs — by delivering precise information about the type of infection present.

Do you have any pet owner-facing materials I can use to help educate my clients about the need for preventive parasite screening?

Great question! We have a special toolkit all about the importance of regular fecal screenings coming soon. Be sure to get in touch with your Antech rep or fill out the contact form to receive the toolkit as soon as it launches.

Real-World KeyScreen Stories

Otis’ Hookworm Story

After two rounds of unsuccessful treatment for a hookworm infection, KeyScreen detected the hookworm treatment-resistance marker that was stopping Otis from getting better.

Misha’s Giardia. Story

When this rescued kitten returned to his veterinarian with severe diarrhea and other persistent symptoms, KeyScreen detected a potentially zoonotic strain of Giardia..

Understand parasite risk in your region. View CAPC parasite prevalence maps for dogs and cats.

Interested or have questions? Connect with a rep.

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1“Parasite Testing and Protection Guided by Veterinarians”, CAPC, last modified April 24, 2025, https://capcvet.org/guidelines/general-guidelines/

2Leutenegger, C.M., Lozoya, C.E., Tereski, J. et al. Comparative study of a broad qPCR panel and centrifugal flotation for detection of gastrointestinal parasites in fecal samples from dogs and cats in the United States. Parasites Vectors 16, 288 (2023). https://doi.org/10.1186/s13071-023-05904-z