{"id":4283,"date":"2023-11-03T15:18:01","date_gmt":"2023-11-03T19:18:01","guid":{"rendered":"\/uncategorized\/case-study-otis-says-so-long-to-hookworms\/"},"modified":"2025-04-29T10:00:08","modified_gmt":"2025-04-29T14:00:08","slug":"etude-de-cas-otis-dit-adieu-aux-ankylostomes","status":"publish","type":"post","link":"https:\/\/uat.antechdiagnostics.com\/fr_ca\/2023\/11\/03\/case-study-otis-says-so-long-to-hookworms\/","title":{"rendered":"\u00c9tude de cas\u00a0: Otis dit \u00ab\u00a0Adieu\u00a0\u00bb aux ankylostomes*\u00a0"},"content":{"rendered":"<div style=\"height:53px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-color\" style=\"color:#463797\"><strong><strong>D\u00e9tails du cas<\/strong>&nbsp;<\/strong><\/h2>\n\n\n\n<p class=\"has-text-color\" style=\"color:#3d4543\"><strong>Otis : <\/strong>Bullmastiff m\u00e2le intact de 4 mois&nbsp;<\/p>\n\n\n\n<p class=\"has-text-color\" style=\"color:#3d4543\"><strong>Emplacement:<\/strong> Ontario, Canada&nbsp;<\/p>\n\n\n\n<p class=\"has-text-color\" style=\"color:#3d4543\"><strong>Arri\u00e8re-plan: <\/strong>Otis vit en dehors de la ville ; il n&#039;a jamais voyag\u00e9 aux \u00c9tats-Unis, n&#039;a pas \u00e9t\u00e9 en contact avec d&#039;autres chiens et n&#039;a jamais \u00e9t\u00e9 dans un chenil en pension.&nbsp;<\/p>\n\n\n\n<p class=\"has-text-color\" style=\"color:#3d4543\"><strong>V\u00e9t\u00e9rinaire principal :<\/strong>Dr Tai Deluna \u2014 Services v\u00e9t\u00e9rinaires Abernant&nbsp;<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-color\" style=\"color:#463797\"><strong><strong><strong>Les ant\u00e9c\u00e9dents m\u00e9dicaux d&#039;Otis<\/strong>&nbsp;<\/strong><\/strong><\/h2>\n\n\n\n<p class=\"has-text-color\" style=\"color:#3d4543\"><strong>Visite initiale et traitement (d\u00e9but 2023) :<\/strong>&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Il pr\u00e9sentait une diarrh\u00e9e et un retard de croissance (maigre et sous-d\u00e9velopp\u00e9)&nbsp;<\/li>\n\n\n\n<li>L&#039;\u00e9quipe a effectu\u00e9 une flottaison f\u00e9cale en interne qui s&#039;est r\u00e9v\u00e9l\u00e9e positive \u00e0 l&#039;ankylostome.&nbsp;<\/li>\n\n\n\n<li>Otis a \u00e9t\u00e9 trait\u00e9 avec un m\u00e9dicament antiparasitaire&nbsp;<\/li>\n<\/ul>\n\n\n\n<p><strong>Au cours des 2 \u00e0 3 prochaines semaines :<\/strong>&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Une semaine apr\u00e8s son traitement initial, une nouvelle flottaison f\u00e9cale s&#039;est r\u00e9v\u00e9l\u00e9e positive \u00e0 l&#039;ankylostome.&nbsp;<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Otis a \u00e9t\u00e9 trait\u00e9 une deuxi\u00e8me fois avec le m\u00eame m\u00e9dicament antiparasitaire&nbsp;<\/li>\n\n\n\n<li>Une semaine apr\u00e8s son deuxi\u00e8me traitement, lors de sa troisi\u00e8me flottaison f\u00e9cale, Otis \u00e9tait toujours positif \u00e0 l&#039;ankylostome&nbsp;<\/li>\n<\/ul>\n\n\n\n<p><strong>6 semaines apr\u00e8s la premi\u00e8re visite d&#039;Otis :<\/strong>&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Il avait toujours la diarrh\u00e9e et \u00e9tait tr\u00e8s maigre.&nbsp;<\/li>\n\n\n\n<li>Un \u00e9chantillon f\u00e9cal a \u00e9t\u00e9 envoy\u00e9 \u00e0 Antech pour un test KeyScreen\u00ae GI Parasite PCR&nbsp;<\/li>\n<\/ul>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-color\" style=\"color:#463797\"><strong><strong><strong>R\u00e9sultats du parasite gastro-intestinal KeyScreen PCR<\/strong>&nbsp;<\/strong><\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><em>Ancylostome<\/em> spp. d\u00e9tect\u00e9es&nbsp;&nbsp;&nbsp;<\/li>\n\n\n\n<li>Marqueur de r\u00e9sistance au traitement contre l&#039;ankylostome d\u00e9tect\u00e9&nbsp;<\/li>\n\n\n\n<li><em>Giardia duod\u00e9nal <\/em>d\u00e9tect\u00e9<em>&nbsp;<\/em>&nbsp;<\/li>\n\n\n\n<li><em>Giardia. <\/em>marqueur d&#039;assemblage zoonotique potentiel non d\u00e9tect\u00e9&nbsp;<\/li>\n<\/ul>\n\n\n\n<p>Le v\u00e9t\u00e9rinaire d&#039;Otis a parl\u00e9 \u00e0 un sp\u00e9cialiste en m\u00e9decine interne du Antech, qui a collabor\u00e9 avec son \u00e9quipe v\u00e9t\u00e9rinaire sur un ensemble personnalis\u00e9 de recommandations fond\u00e9es sur des preuves et des experts pour son traitement, les pr\u00e9occupations de One Health (zoonoses, fardeau environnemental) et la gestion des antimicrobiens.&nbsp;&nbsp;<\/p>\n\n\n\n<div style=\"height:39px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-color\" style=\"color:#463797\"><strong><strong><strong><strong>Otis a commenc\u00e9 une th\u00e9rapie antiparasitaire cibl\u00e9e<\/strong><\/strong><\/strong><\/strong><\/h2>\n\n\n\n<p>La diarrh\u00e9e d\u2019Otis s\u2019est am\u00e9lior\u00e9e deux jours apr\u00e8s le d\u00e9but du traitement et, au troisi\u00e8me jour, ses selles \u00e9taient tout \u00e0 fait normales.&nbsp;<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-color\" style=\"color:#463797\"><strong><strong><strong><strong><strong>Parasite gastro-intestinal KeyScreen R\u00e9sultat PCR \u2014 3 semaines apr\u00e8s le traitement cibl\u00e9 :<\/strong>\u202f&nbsp;<\/strong><\/strong><\/strong><\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><em>Ancylostome<\/em> spp. non d\u00e9tect\u00e9&nbsp;<\/li>\n\n\n\n<li><em>Giardia duod\u00e9nal<\/em> d\u00e9tect\u00e9&nbsp;<\/li>\n\n\n\n<li><em>Giardia.<\/em> marqueur d&#039;assemblage zoonotique potentiel non d\u00e9tect\u00e9&nbsp;<\/li>\n<\/ul>\n\n\n\n<p>Un mois apr\u00e8s avoir commenc\u00e9 un traitement cibl\u00e9 contre son ankylostomiase r\u00e9sistante, Otis se portait bien. Ses selles \u00e9taient parfaitement normales, son poids et sa masse musculaire avaient augment\u00e9 de fa\u00e7on impressionnante, et son \u00e9quipe soignante \u00e9tait ravie de le voir sur la voie d&#039;une gu\u00e9rison compl\u00e8te.&nbsp;<\/p>\n\n\n\n<p><strong>Neuf mois apr\u00e8s sa premi\u00e8re visite, Otis se porte \u00e0 merveille.<\/strong>&nbsp;<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-color\" style=\"color:#463797\"><strong><strong><strong><strong><strong><strong>KeyScreen Parasite gastro-intestinal PCR Impact du bo\u00eetier pour Otis<\/strong>&nbsp;<\/strong><\/strong><\/strong><\/strong><\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>D\u00e9tection du marqueur de r\u00e9sistance au traitement de l&#039;ankylostome au benzimidazole (par exemple, le fenbendazole), qui \u00e9tait probablement la cause de l&#039;\u00e9chec du traitement d&#039;Otis et de la persistance de l&#039;ankylostome&nbsp;<\/li>\n\n\n\n<li>La d\u00e9tection a conduit \u00e0 un traitement pr\u00e9cis et cibl\u00e9 contre l&#039;ankylostome par l&#039;\u00e9quipe de soins d&#039;Otis&nbsp;<\/li>\n\n\n\n<li>R\u00e9solution des signes cliniques \u2014 Otis est maintenant un chiot heureux et en bonne sant\u00e9&nbsp;<\/li>\n\n\n\n<li>Utilisation et gestion appropri\u00e9es des antimicrobiens&nbsp;<\/li>\n\n\n\n<li><a href=\"https:\/\/www.cdc.gov\/onehealth\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">Une seule sant\u00e9<\/a> responsabilit\u00e9 envers l&#039;animal, les humains et l&#039;environnement&nbsp;<\/li>\n\n\n\n<li>Confirmation de la r\u00e9solution de l&#039;infection par l&#039;ankylostome apr\u00e8s le traitement&nbsp;<\/li>\n\n\n\n<li>Assurance d&#039;un assemblage potentiel non zoonotique <em>Giardia.<\/em>&nbsp;<\/li>\n\n\n\n<li>L&#039;absence de signes cliniques chez Otis (selles normales) a assur\u00e9 \u00e0 son \u00e9quipe soignante qu&#039;il n&#039;y avait pas besoin de traitement m\u00e9dicamenteux sp\u00e9cifique pour <em>Giardia. <\/em>ou pr\u00e9occupation pour les propri\u00e9taires d&#039;Otis&nbsp;<\/li>\n<\/ul>\n\n\n\n<div style=\"height:43px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-color\" style=\"color:#463797\"><strong><strong><strong><strong><strong><strong>Obtenez des informations plus approfondies, une d\u00e9tection plus rapide de l\u2019infection et des plans de traitement personnalis\u00e9s. <\/strong>&nbsp;<\/strong><\/strong><\/strong><\/strong><\/strong><\/h2>\n\n\n\n<p><strong>Utilisez KeyScreen\u00ae GI Parasite PCR d\u00e8s aujourd\u2019hui.&nbsp;<\/strong>&nbsp;<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-width wp-block-button__width-25 is-style-fill\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"\/fr_ca\/laboratoire-de-reference\/diagnostic\/parasite-gastro-intestinal-sur-ecran-tactile-pcr\/\" style=\"background-color:#463797\" target=\"_blank\" rel=\"noreferrer noopener\">En savoir plus<\/a><\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-black-color has-css-opacity has-black-background-color has-background aligncenter is-style-wide\"\/>\n\n\n\n<div style=\"height:43px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading has-black-color has-text-color\"><strong>D\u00e9couvrez nos \u00e9tudes \u00e9valu\u00e9es par des pairs KeyScreen sur l&#039;ankylostome<\/strong><\/h3>\n\n\n\n<p>*Evason, MD, et al. \u00c9mergence de la r\u00e9sistance au traitement contre l&#039;ankylostome canin : nouvelle d\u00e9tection de <em>Ancylostoma caninum<\/em> Marqueurs de r\u00e9sistance aux anthelminthiques par PCR f\u00e9cal chez 11 chiens du Canada, Am J Vet Res<em>.<\/em>2023 : <a href=\"https:\/\/doi.org\/10.2460\/ajvr.23.05.0116\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.2460\/ajvr.23.05.0116<\/a>&nbsp;<\/p>\n\n\n\n<p>Leutenegger CM, et al. \u00c9tude comparative d&#039;un large panel qPCR et de la flottation centrifuge pour la d\u00e9tection de parasites gastro-intestinaux dans des \u00e9chantillons f\u00e9caux de chiens et de chats aux \u00c9tats-Unis. Parasites et vecteurs. 2023.&nbsp;<\/p>\n\n\n\n<p><a href=\"https:\/\/parasitesandvectors.biomedcentral.com\/articles\/10.1186\/s13071-023-05904-z\" rel=\"noopener\">https:\/\/parasitesandvectors.biomedcentral.com\/articles\/10.1186\/s13071-023-05904-z<\/a><\/p>\n\n\n\n<p>Leutenegger CM, et al. \u00c9mergence de <em>Ancylostoma caninum<\/em> parasites pr\u00e9sentant le polymorphisme F167Y de r\u00e9sistance au benzimidazole dans la population canine am\u00e9ricaine. Int. J. Parasitol. Drugs Drug Resist.2023;14:131-140. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211320723000015?via%3Dihub\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211320723000015?via%3Dihub<\/a>&nbsp;<\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>D\u00e9tails du cas\u00a0: Otis\u00a0: Bullmastiff m\u00e2le entier de 4\u00a0mois. Lieu\u00a0: Ontario, Canada. Contexte\u00a0: Otis vit en p\u00e9riph\u00e9rie de la ville\u00a0; il n\u2019a jamais voyag\u00e9 aux \u00c9tats-Unis, n\u2019a jamais \u00e9t\u00e9 en contact avec d\u2019autres chiens et n\u2019a jamais \u00e9t\u00e9 en pension. V\u00e9t\u00e9rinaire traitant\u00a0: Dr\u00a0Tai Deluna \u2014 Abernant Veterinary Services. Ant\u00e9c\u00e9dents m\u00e9dicaux d\u2019Otis\u00a0: Premi\u00e8re consultation et traitement [\u2026]<\/p>","protected":false},"author":5,"featured_media":4284,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"categories":[57],"tags":[],"service-area":[42],"class_list":["post-4283","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-case-studies","service-area-reference-lab"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-13 12:01:17","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/uat.antechdiagnostics.com\/fr_ca\/wp-json\/wp\/v2\/posts\/4283","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/uat.antechdiagnostics.com\/fr_ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/uat.antechdiagnostics.com\/fr_ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/uat.antechdiagnostics.com\/fr_ca\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/uat.antechdiagnostics.com\/fr_ca\/wp-json\/wp\/v2\/comments?post=4283"}],"version-history":[{"count":0,"href":"https:\/\/uat.antechdiagnostics.com\/fr_ca\/wp-json\/wp\/v2\/posts\/4283\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/uat.antechdiagnostics.com\/fr_ca\/wp-json\/wp\/v2\/media\/4284"}],"wp:attachment":[{"href":"https:\/\/uat.antechdiagnostics.com\/fr_ca\/wp-json\/wp\/v2\/media?parent=4283"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/uat.antechdiagnostics.com\/fr_ca\/wp-json\/wp\/v2\/categories?post=4283"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/uat.antechdiagnostics.com\/fr_ca\/wp-json\/wp\/v2\/tags?post=4283"},{"taxonomy":"service-area","embeddable":true,"href":"https:\/\/uat.antechdiagnostics.com\/fr_ca\/wp-json\/wp\/v2\/service-area?post=4283"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}